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Rus Bio - Stanozolol is a dihydrotestosterone (DHT) derived anabolic androgenic steroid, or more specifically a structurally altered form. Rus Bio Stanozolol is the DHT hormone with two structural changes that give us the Winstrol compound.The first alteration is the introduction of an attached pyrazol group at the A-ring of the hormone replacing the 3-keto group. This modification officially classifies Rus Bio Stanozolol as a heterocyclic steroid. The hormone also carries an added methyl group in order to protect hormone after administration. This structural change takes place at the 17th carbon position officially classifying Stanozolol as a C17-alpha alkylated (C17-aa) anabolic steroid.
History and Overview of Rus Bio Stanozolol
Winstrol is the trade name and brand name for the anabolic steroid more formally and properly known as Stanozolol. It exists in both an oral and injectable format, and it sits on the third place pedestal among the top 3 anabolic steroids most widely used and most popular among bodybuilders and athletes. It is superseded only by Deca-Durabolin (Nandrolone Decanoate) in second place, and Dianabol (Methandrostenolone) in first place. Winstrol is probably most famous and well-known for its alleged use by Canadian Olympic sprinter Ben Johnson in the 1988 Seoul Summer Olympic games where he tested positive for it. However, its origins begin in 1959 when its details were first released in the medical and scientific community. It was Winthrop Laboratories in the UK that marketed Stanozolol on the prescription drug market, and Sterling in the USA ended up buying the patent in 1961 for the US market where it was branded as Winstrol.
Winstrol was approved for an extensive list of medical treatments following its release onto the prescription drug market, ranging from tissue and muscle wasting diseases to an Oesteoporosis drug, as well as in the treatment of burn victims and children with stunted growth. Winstrol was not very effective as a treatment for anemia, however. Winstrol’s mechanism of action is quite brilliant in several different ways. Its primary operation is through binding with the androgen receptor rather than non-receptor mediated activity, which is common with certain other anabolic steroids such as Dianabol or Anadrol. Winstrol also has a low affinity for binding with the Glucocorticoid-binding sites in addition to some activity that is independent of androgen receptors. Winstrol also possesses a very low degree of Progestogenic activity in the body.
An impressive and somewhat unique function that Winstrol exhibits is its ability to significantly lower SHBG (Sex Hormone Binding Globulin) levels in the body, allowing freer Testosterone and other anabolic hormones to be able to exert anabolic activity in muscle tissues. It exhibits exceptional capability and a high degree of stimulating and facilitating protein synthesis. Winstrol has also been observed to possess a capability of boosting collagen synthesis in the body.
Side Effects of Rus Bio Stanozolol
The primary areas of concern when it comes to Rus Bio Stanozolol side effects are, simply put: hepatic (liver) issues relating to hepatotoxicity, HPTA (Hypothalamic Pituitary Testicular Axis) disruption, and negative cardiovascular system impacts.
Because Rus Bio Stanozolol is a DHT-derived anabolic steroid, it cannot convert into Estrogen at any dose. This means that no Estrogenic side effects should be experienced as a result of Rus Bio Stanozolol use alone. Therefore, side effects such as gynecomastia, water retention and bloating, or other side effects as a result of Estrogen buildup are completely nonexistent here.
Although Rus Bio Stanozolol does possess a weaker androgenic strength rating than Testosterone does, androgenic side effects are still a potential risk, though much lower, and may only effect users significantly if they are especially sensitive to androgens. Androgenic side effects can include increased oily skin and acne, hair growth on the body, MPB (male pattern baldness), and BPH (Benign Prostatic Hypertrophy). The use of a 5-alpha reductase (5AR) inhibitor, such as Finasteride, Dutasteride, Proscar, or Propecia will be completely ineffective here, as Rus Bio Stanozolol does not convert into DHT.
One area of prominent concern is that of HPTA suppression, which is a given with the use of any anabolic steroid. Studies have demonstrated that with even as low as 10mg/day of Rus Bio Stanozolol, subjects experienced a 55% decrease in endogenous Testosterone production after only 14 days. Hepatotoxicity (liver toxicity) is also one effect that one should be conscious of with Rus Bio Stanozolol, especially with use of the oral variant. The injectable preparation of Winstrol has also raised concerns in studies, where severe hepatotoxicity was eventually experienced by otherwise healthy individuals. It is therefore recommended to utilize Rus Bio Stanozolol, especially the oral variant, for periods of no longer than 6 – 8 weeks at a time.
Cardiovascular health concerns are particularly major when it comes to Rus Bio Stanozolol side effects. First and foremost, Rus Bio Stanozolol is notorious for producing very severe and dangerous negative alterations in blood cholesterol levels, even with miniscule dosages of the oral format (as low as 6mg/day). Even the injectable preparation of Stanozolol has demonstrated very negative implications on blood cholesterol. To add further concern to Winstrol’s cardiovascular effects, evidence suggests that it can also stimulate cardiac hypertrophy at even small dosages.
|Dosage||Men 50-100 mg/day|
|Active half-life||8 hours|